RAC1 and cancer: These Rac1-interacting factors include proteins with a range of functions, such as kinases, receptor kinases, two guanine nucleotide exchange factors that activate Rac1, chaperones and co-chaperones, a transcription factor, and a receptor for protein kinase C that in animals acts as a scaffolding protein with important roles in development, ageing, cancer, and various signalling processes (Akamatsu et al., 2013; Chen et al., 2010; Lieberherr et al., 2005; Nakashima et al., 2008; Thao et al., 2007; Wamaitha et al., 2012; Yamaguchi et al., 2012; Yamaguchi et al., 2013).