A direct implication of MAOB in schizophrenia is supported by several studies (Coron et al., 1996; Bergen et al., 2009; Carrera et al., 2009; Piton et al., 2011; Wei et al., 2011; Sun et al., 2012a) and may be reflective of the greater contribution of this enzyme to the metabolism of DA in humans. The gene discussed is MAOB; the disease is schizophrenia.