RRM2 and cancer: The RRM2 expression in the cancer tissues was higher than that in high-grade dysplasia (median H score: 1.0 vs. 0.5; Hommel's adjusted p<0.001), low-grade dysplasia (median H score: 1.0 vs. 0.5; Hommel's adjusted p = 0.002) or normal (median H score: 1.0 vs. 0.5; Hommel's adjusted p<0.001) tissues.