In order to identify which ADAR (ADAR1 and/or ADAR2) was responsible for the editing events found in the OPHN1 transcript, we took advantage of the astrocytoma cell lines (U118 and U87) available in our laboratory, in which we stably modulate the expression of the ADAR enzymes. Here, ADAR is linked to astrocytoma (excluding glioblastoma).