To determine whether Blk-haploinsufficiency and Blk-deficiency also have different effects on γδ-17 cell function, we compared the in vivo γδ-17 response in B6, Blk+/− and Blk−/− mice following infection with Listeria monocytogenes, a model pathogen known to elicit a robust γδ-17 response [55]. This evidence concerns the gene BLK and infection.