It has been reported that MYC and BCL2 act synergistically to promote primary cells into tumour cells [58], while in our work, MYC is dependent on BCL2 to influence the outcome of breast cancer (with p-value of 0.0119) and BCL2 also relies on MYC significantly (with p-value of 0.0388). The gene discussed is MYC; the disease is breast carcinoma.