FOXP3 and Patent ductus arteriosus: The multivariate analysis indicated that the intratumoral density of Foxp3+ cells (hazard ratio (HR) = 0.3162, P<0.0001), histologic grade (HR = 0.3189, P = 0.0018, Figure 4B) and TNM stage (HR = 0.2185, P = 0.0162, Figure 4C) were independent prognostic factors for the PDA patient overall survival.