We injected Ad-NDRG2 at the concentrations of 0.5, 1 and 2 × 109 PFU or 2 × 109 PFU Ad-LacZ every 3 days into preestablished human SK-BR-3 breast tumours (approximately 200 mm3) grown in nude mice. The gene discussed is NDRG2; the disease is breast neoplasm.