NFKB1 and Hyperbilirubinemia: In both Kupffer cells and lymphocytes, NF-κB p65 expression was significantly increased in the group with severe P. falciparum malaria with hyperbilirubinaemia, compared with non-hyperbilirubinaemia group (p = 0.030 and p = 0.009, respectively) and normal controls (all p < 0.001).