Reexpression of 15-LOX-1 by Ad-15-LOX-1 also reduced tumor cell invasion of HCT116 by 94 ± 8.1% and of LoVo by 98 ± 3% compared with the cells transfected with Ad-luciferase (Figs. 4E–H). This evidence concerns the gene OLR1 and neoplasm.