GPT and cancer: In younger adults, moderately elevated HRs of all-cause mortality (HR: 1.06, 95% CI: 1.06–1.07), CV-related mortality (HR: 1.03, 95% CI: 1.02–1.05), and cancer-related mortality (HR: 1.07, 95% CI: 1.06–1.08) per 5 U/l of ALT increment were observed with significant heterogeneity (Figure 2).