CXCL10/CXCR3 signaling has also been implicated in GBS pathogenesis based on a report that demonstrated elevated CSF CXCL10 levels in GBS patients compared to controls, with CXCL10 messenger RNA co-localized to peripheral nerve vascular endothelium using in situ hybridization techniques [38]. This evidence concerns the gene CXCL10 and Guillain-Barre syndrome.