It is provocative to speculate that inflammatory changes at the blood-nerve barrier may be associated with increased nerve root cerebrospinal fluid (CSF) chemokine secretion, based on observational data that showed a correlation between CSF CXCL10 and CCL2 levels and increased CSF: plasma albumin ratios in GBS [6]. This evidence concerns the gene CXCL10 and Guillain-Barre syndrome.