BCL2 and melanoma: The expression of pro and antiapoptotic factors respectively Bax and Bcl2 were found to be reciprocally regulated by PKC α and PKCδ overexpression and more importantly the ratio between Bax/Bcl2 was found to be tilted towards cellular apoptosis in PKCδOV melanoma cell, which is otherwise deregulated in growing B16F10 melanoma cells.