TP53 and cancer: The phosphatase and tensin homolog (PTEN), v-akt murine thymoma viral oncogene homolog 1 (AKT1), mouse double minute 2 (MDM2) and p53 tumor suppressor-oncoprotein network plays a crucial role in regulating a number of cellular processes such as cell growth, apoptosis, survival and cell cycle, which ultimately contributes to cancer development and progression [6]–[8].