Some genes were closely related to the malignant phenotype of the tumor, such as IGF1, CXCR7, TCF3, NPR1, FGF18, DDR2, GLI2, CYR61, COL14A1, HSPH1, SOX11, TRIB2, PDZK1, and MMP2. The gene discussed is CCN1; the disease is neoplasm.