In NSCLC cells, upon stimulation with HGF, we observed a strong nuclear colocalization of PAX8 and phosphorylated MET and RON in the nucleus and a similar colocalization was also seen in C. elegans eggs suggesting that this soil nematode can be used a model to study the genetics of MET/PAX8 and signaling axis. Here, MST1R is linked to non-small cell lung carcinoma.