NR4A3 and neuroblastoma: We analyzed methylation level of human homologous region (chr4:48072371-48072905, in USCS genome database, March, 2006, NCBI36/hg18) in the surgical resected NB specimens and found that all 3 NB specimens showed significantly lower methylation level at NR4A3 exon 3 CpGi compare to those from the matched adrenal tissues (Fig. 2).