ZEB2/SIP1, as a member of the deltaEF-1 family of two-handed zinc-finger factors, is frequently expressed in a variety of human cancers, including pancreatic [31], breast [32], gastric [33], [34], renal [35], head and neck [36], glioma [37], hepatocellular [38], ovarian [39], squamous and non-small cell lung carcinomas [14], [15]. The gene discussed is ZEB2; the disease is cancer.