TNFSF10 and Familial prostate cancer: Although our report does not address the expression of TRAIL receptors, we cite a paper that demonstrated the upregulation of the death receptors DR4 and DR5 in TRAIL-resistant PC3 and LNCap prostate cancer cells by sulforaphane, which enhanced TRAIL-induced apoptosis in vitro and in orthotopically growing PC3 xenografts transplanted into the prostate gland of immunodeficient mice (8).