WRAP53 and esophageal squamous cell carcinoma: To investigate the relationship between WRAP53 expression and ESCC, we first examined the expression of WRAP53 in 4 ESCC cell lines (EC109, EC9706, KYSE150, and KYSE180) we detected the expression of WRAP53 protein in all 4 ESCC cell lines with an expected molecular weight of 75 kDa(Figure 1).