CASP1 and infection: Three and twelve hours after infection with B. pseudomallei E8 led to a stronger caspase-1 and -7 activation compared to B. thailandensis E264 in the wild-type as well as to a strong cleavage signal of caspase-7 in the caspase-1/11 knockout indicating that activation of caspase-7 is independent of caspase-1/11 at later stages of infection.