Furthermore, infection of mouse macrophage cell lines stably expressing rat NLRP1 constructs also did not result in sensitization to Toxoplasma (Figure S8, panel B), suggesting the presence of other factors in murine macrophages, or the BMAJ macrophage cell line, that result in a dominant resistance to pyroptosis or the absence of a factor needed for interaction with rat NLRP1 and subsequent pyroptosis. Here, NLRP1 is linked to infection.