In addition, genome-wide association studies (GWAS) using large cohorts of patients and control subjects have identified single nucleotide polymorphisms (SNPs) in CACNA1C (alpha 1C subunit of the L-type voltage-gated calcium channel) and ANK3 (ankyrin 3) implicating these as potential susceptibility genes for bipolar disorder [4]–[6]. Here, ANK3 is linked to bipolar disorder.