RAN and ovarian serous carcinoma: Figure 1 shows representative images for the staining of each protein in HG serous ovarian carcinomas. Expression of RAN (Figure 1A–C), RANBP1 (Figure 1D–F) and IMPβ (Figure 1J–L) were localized to both the cytoplasm and the nucleus, although signal quantification focused exclusively on the cytoplasm based on its higher expression in this cellular compartment. Expression of RCC1 (Figure 1G–I) and TPX2 (Figure 1Y–Z) were nuclear. Nuclear and cytoplasmic staining was observed for XPO7 (Figure 1M–R) and XPOT (Figure 1S–X) proteins, and both were quantified.