ZEB1 and neoplasm: More recent approaches have centered on a series of molecules known as potentially regulating tumor progression such as microRNA-200c (miR200c) [12] and zinc finger E-box binding homeobox 1 (ZEB1) [13], which have provided proofs that overexpression of miR200c or knockdown of ZEB1 could repress tumor ‘epithelial to mesenchymal transition’ (EMT) program that activates cellular mobility, subsequent tumor metastasis [14-16].