CGRP peripheral expression was significantly reduced in neuropathic patients with lesions versus C (N2 13 ± 2.2, N1 17 ± 2.2, N 18 ± 2.8, P < 0.004, P < 0.04, P < 0.09, resp., versus C 26 ± 2 pg/mL) and it was negatively correlated in all T2DM with CD34+CD45− (P < 0.01  R2 = −0.2) and CD34+KDR+ (P < 0.007  R2 = −0.2). Here, PTPRC is linked to type 2 diabetes mellitus.