Indeed, according to Slater et al, PALB2 mutation carriers in FPC families demonstrated a 10- to 32-fold increased risk for the development of pancreatic cancer depending on the number of affected family members (Brand et al., 2007; Rahman et al., 2007; Jones et al., 2009; Slater et al., 2010). The gene discussed is PALB2; the disease is familial pancreatic carcinoma.