It has been hypothesized that these results may be due to a decrease in tumor vasculature mediated through endothelial apoptosis, given that EGFR is expressed not only on tumor cells but also on dividing endothelial cells (Bruns et al., 2000; Li et al., 2004b; Ducreux et al., 2007). The gene discussed is EGFR; the disease is neoplasm.