STAR and congenital lipoid adrenal hyperplasia due to STAR deficency: STAR mutations in humans have a clear effect on steroidogenesis with a phenotype ranging from severe lipoid congenital adrenal hyperplasia (LCAH), involving both adrenal and gonadal dysfunction to milder atypical or non-classic forms of LCAH which can resemble FGD (Baker et al. 2006, Metherell et al. 2009, Miller 2011).