Several CD4+ and CD8+ T cell clones obtained from the blood of acute and convalescent HPS patients recognize epitopes from N, Gn and Gc viral proteins (Ennis et al. 1997; Kilpatrick et al. 2004; Terajima et al. 2004; Van Epps et al. 1999). This evidence concerns the gene CD8A and Hermansky-Pudlak syndrome.