CDKN2B and colorectal carcinoma: We note that the fold-increase of p14ARF, p15INK4B, and p16INK4A expression following knockdown of ZNF304 or repressive cofactors in H9 hESCs was less than that observed in KRAS-positive CRC cell lines, but is entirely consistent with results of other studies analyzing the role of INK4-ARF repressors in non-malignant cells (e.g., Bracken et al., 2007).