We next used a pathology tissue ChIP (PAT-ChIP) assay (Fanelli et al., 2011) to measure association of ZNF304 with p14ARF, p15INK4B, and p16INK4A promoters in KRAS-positive human CRC tumor samples and, as a control, adjacent matched normal colon. The gene discussed is CDKN2B; the disease is neoplasm.