Remarkably, KDM6A mutations were found to be widespread across both solid and liquid tumors, including AML, chronic myelogenous leukemia (CML), T-ALL, MM, Hodgkin’s lymphoma (HL), TCC, breast, colon, esophageal, pancreas, endometrial, GBM, small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC), and RCC (Dalgliesh et al., 2010; Gui et al., 2011; Mann et al., 2012; Mar et al., 2012; Ross et al., 2013; van Haaften et al., 2009). The gene discussed is KDM6A; the disease is Hodgkins lymphoma.