We also detected some biological markers in the diagnosis of recurrent bladder cancer was dysregulated in UCB, including KRT20 (Cytokeratin 20) [35], BIRC5 (Survivin) [36], [37], CDH1 (E-cadherin) [38] and PSCA (Prostate Stem Cell Antigen-14) [39], [40]. The gene discussed is CDH1; the disease is urinary bladder carcinoma.