For example, miR-196a has been studied for its oncogenic roles in glioblastoma, pancreatic adenocarcinoma, breast cancer, oesophageal adenocarcinoma, and colorectal cancer, and shown to target HOX family genes (HOXA7, HoxB7, HOXC8, HOXB8, HOXD8), ERG, HMGA2, ANXA1, S100A9, SPRR2C, KRTS [25], [26]–[31]. This evidence concerns the gene S100A9 and esophageal adenocarcinoma.