We showed that the developmental transcription factor TFCP2L1 (transcription factor CP2-like 1) whose loss was recently suggested to play a role in the loss of epithelial differentiation and function in ccRCC, is a true target of miR-489, which was among the ccRCC-specific miRNAs in our study [54]. Here, TFCP2L1 is linked to nonpapillary renal cell carcinoma.