CR1 and non-small cell lung carcinoma: As shown in Table 4, the risk of NSCLC was associated with the rs7525160 C allele carriers in smokers with OR (95% CI) of 1.72 (1.15-2.59), but not in non-smokers with OR (95% CI) of 1.15 (0.81-1.65), suggesting that the CR1 rs7525160 G > C polymorphism is a smoking-modifying risk factor for susceptibility to NSCLC.