PAK2 and metastatic malignant neoplasm in the lymph nodes: The univariate analysis showed that the following factors were significantly related to postoperative survival: depth of tumor invasion (P < 0.001), lymph node metastasis (P < 0.001), venous invasion (P < 0.001), PAK2 expression (P = 0.001) and pSer20PAK2 expressions (P = 0.001).