CASP3 and uterine corpus sarcoma: In order to compare the effectiveness of the previously published single SAHA treatment [16] to apoptosis induction by SAHA/TRAIL or single TRAIL treatment, we monitored the activation of effector caspases-3, -6, and -7, as well as the the initiator caspase-8 in uterine sarcoma cells (Fig. 3).