We have recently developed a caspase-3/7-specific probe, 18F-(S)-1-((1-(2-fluoroethyl)-1H-[1], [2], [3]triazol-4-yl)methyl)-5-(2(2,4-difluorophenoxymethyl)-pyrrolidine-1-sulfonyl)isatin (18F-ICMT-11), for the in vivo imaging of therapy-induced tumour apoptosis. Here, CASP3 is linked to neoplasm.