On the one hand, CUX1 is located in the 7q22.1 chromosomal region, which is the target of loss-of-heterozygosity in a number of cancers [20]–[22], and recent studies have pointed to CUX1 being as the putative tumor suppressor on 7q22.1 [23]–[26]. Here, CUX1 is linked to neoplasm.