GSK3B and non-small cell lung carcinoma: In these tumor tissues, nuclear GSK3β might play a role in NF-κB -mediated cancer cell survival; however, after knockdown of GSK3β, the NF-κB expression levels in the different NSCLC cell lines of our study were inconsistent, indicating that GSK3β may mediate cancer cell survival independent of NFκB expression (data not shown).