IL4 and Increased total eosinophil count: We used a dexamethasone treatment protocol that reduced OVA-induced eosinophilia and IL-4 production in the lung by greater than 95% when given 1 h prior to allergen challenge in an acute 4 week asthma model (3 x OVA + alum intraperitoneal followed by 2 airway challenges, data not shown) and also strongly reduced the lung inflammation when OVA was used as allergen in a chronic model (Figure S2).