HAMP and Tangier disease: Since the characterization of iron export above was performed in a hepcidin-free medium, which does not correspond to most in vivo situations in which NTBI is present, we re-analyzed iron export by T lymphocytes, using the same experimental setup, in the presence of human synthetic hepcidin at doses present in human serum in normal and in iron-overload conditions (Ganz et al., 2008).