We next determined if E1A-OVA expression in MCA-205 tumor cells retained E1A in vivo biological activity by measuring the tumorigenicity of MCA-205, MCA-205-E1A, MCA-205-OVA, MCA-205-E1A-Δp300-OVA and MCA-205-E1A-OVA tumor lines (Figure 2). Here, DHTKD1 is linked to neoplasm.