Although there was no significant difference in the percentage of OT-I cells in the popliteal lymph node following challenge with MCA-205-OVA, MCA-205-E1A-Δp300-OVA or MCA-205-E1A-OVA tumor cells (Figure 3 A), MCA-205-OVA or MCA-205-E1A-Δp300-OVA tumor cells had a significantly higher number of OT-I cells compared to mice challenged with MCA-205-E1A-OVA tumor cells (Figure 3 B). The gene discussed is DHTKD1; the disease is neoplasm.