MCA-205-OVA and MCA-205-E1A-Δp300-OVA tumor cells were equivalently tumorigenic as MCA-205 tumor cells, indicating that expression of either OVA or E1A-Δp300-OVA in MCA-205 cells does not alter the intrinsic tumorigenicity of the MCA-205 line. The gene discussed is DHTKD1; the disease is neoplasm.