HIF1A and gastric cancer: In a meta-analysis performed by Zhang et al. [22], involving 12 trials (1,555 patients), it was reported that HIF-1α expression was significantly correlated with poor overall survival of gastric cancer patients (HR = 1.34, 95%CI: 1.13–1.58; P = 0.0009), but not with poor disease free survival of gastric cancer patients (HR = 1.67, 95%CI: 0.99–2.82; P = 0.06).