The differential diagnosis for genetic dystonia parkinsonism continues to grow with an ever expanding number of causes and syndromes identified in both infants/children (neurotransmitter defects, metal storage diseases, mitochondrial disorders, lysosomal storage disorders) (García-Cazorla et al., 2011) and adolescents/adults (parkin, DJ1 and PINK1-related Parkinson’s disease, PLA2G6-associated neurodegeneration, Kufor-Rakeb disease and beta-propeller protein-associated neurodegeneration syndrome) (Schneider and Bhatia, 2010; Haack et al., 2012). Here, PRKN is linked to lysosomal storage disease.