In the prostate cancer model, we analyzed the following cell lines: PC3-EMT14-OVOL1 (OVOL1 overexpression), PC3-EMT14-OVOL2 (OVOL2 overexpression) and PC3-Epi (epithelial cells that express OVOL1 and OVOL2 and from which the mesenchymal PC3-EMT14 were initially obtained) [3]. The gene discussed is OVOL2; the disease is Familial prostate cancer.