DKK1 and non-small cell lung carcinoma: As shown in Figure 2A, among all of the 150 patients with NSCLC, the patients with higher levels of serum DKK-1 had significantly poorer survival than those with lower expression levels of DKK-1, with a 5-year overall survival of 11.27% and 50.42%, respectively (P = 0.0027).