However, we identified a genomic breakpoint (chr10∶114,850,371-114,640,318 (GRCh37)) in the CRC cell line HCT116 that spanned from the intronic region of TCF7L2 to upstream of RP11-57H14.3 (ENSG00000225292) with a corresponding RNA fusion (Table 1). This evidence concerns the gene TCF7L2 and colorectal carcinoma.