The Early Growth Response 1 (EGR1), EGR2 and EGR3, transcription factors that mediate TGF-β-induced signaling, and are highly expressed in fibrosis [31]–[33], were also significantly elevated (2.9-, 6.8- and 10.2-fold, respectively) in SFBLs, while expression of transcriptional EGR repressors, NGFI-A binding protein (NAB) 1 and NAB2 [34], showed no differences (Figure 6A). The gene discussed is EGR3; the disease is fibrosis.