Moreover, CAE has also been reported to be associated with atherosclerotic vascular disease, heterozygous familial hypercholesterolemia, usage of substances inhibitors including herbicide spray, acetylcholinesterase inhibitors and nitrate, prior arterial balloon angioplasty, polyarteritis nodosa and Kawasaki syndrome [1-5]. This evidence concerns the gene ACHE and familial hypercholesterolemia.